Dimethylamine → 4-((Dimethylamino)methyl)phenol

HRID 1848832Notes

Reaction equation

HRID 1848832 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([C:8]2C(C=O)=CC=CC=2)=[CH:4][CH:3]=1.[CH3:16][NH:17][CH3:18].N1(C(OC(C)(C)C)=[O:26])CCNCC1>>[CH3:16][N:17]([CH2:8][C:5]1[CH:6]=[CH:7][C:2]([OH:26])=[CH:3][CH:4]=1)[CH3:18]

Participants

4

Reactant 3

HCID 674DimethylamineHCID 143452tert-Butyl piperazine-1-carboxylateHCID 13936894'-Chlorobiphenyl-2-carbaldehyde

Product 1

HCID 328954-((Dimethylamino)methyl)phenol

Procedure

The title compound was prepared by substituting 4-hydroxybenzaldehyde for 4′-chlorobiphenyl-2-carboxaldehyde and dimethylamine for tert-butyl piperazine-1-carboxylate in EXAMPLE 1A.

Sources & evidence

ORD record
ord-bd491316dd154be18b2a204bb64a7ebc
Source dataset
uspto-grants-2015_02
Patent number
US08952157B2

Reaction notes

Loading…