HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloromethyl Methyl Ether → HCID 67227538, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloromethyl Methyl Ether | HCID 7864 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | HCID 67228558 | HCID 67228558 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 67227538 | HCID 67227538 | — |
Reaction Steps
A mixture of EXAMPLE 158B (0.6 g), chloro(methoxy)methane (0.18 g) and cesium carbonate (0.9 g) was suspended in N,N-dimethylformamide (15 mL). After it stirred at room temperature for 30 minutes, the crude product was purified by preparative HPLC using a 250×50 mm C18 column and eluting with 20-100% CH3CN vs. 0.1% trifluoroacetic acid in water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952157B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-1362640d6187497eb1f87357efb07939 |
| Source note | uspto-grants-2015_02 |