Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1848941Generated: October 30, 2026

(Oxan-4-yl)methanol → 5-bromo-3-fluoro-2-((4-fluorotetrahydro-2H-pyran-4-yl)methoxy)pyridine

https://huagongshe.com/reaction/1848941

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(Oxan-4-yl)methanolHCID 2773573—
Reactant5-Bromo-2,3-difluoropyridineHCID 14549654—
Reactant4-Fluoro-3-nitrobenzenesulfonamideHCID 16782487—
Product5-bromo-3-fluoro-2-((4-fluorotetrahydro-2H-pyran-4-yl)methoxy)pyridineHCID 67126720—

Reaction Steps

This example was prepared by substituting EXAMPLE 296C for (tetrahydro-2H-pyran-4-yl)methanol and 5-bromo-2,3-difluoropyridine for 4-fluoro-3-nitrobenzenesulfonamide in EXAMPLE 264A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08952157B2
Source datasetuspto-grants-2015_02
ORD IDord-df2c619524e04e848d0ad71de7769c91
Source noteuspto-grants-2015_02