HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,10-Phenanthroline → 2,6-Dichlorobiphenyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,10-Phenanthroline | HCID 1318 | — |
| Reactant | 1,3-Dichlorobenzene | HCID 10943 | — |
| Reactant | Iodobenzene | HCID 11575 | — |
| Reactant | HCID 178506942 | HCID 178506942 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Solvent | 2(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl- | HCID 81646 | — |
| Product | 2,6-Dichlorobiphenyl | HCID 36342 | 18% |
Reaction Steps
Copper(I) iodide (19 mg, 0.1 mmol), iodobenzene (204 mg, 1.0 mmol), 1,10-phenanthroline (18 mg, 0.1 mmol), 1,3-dichlorobenzene (220 mg, 1.5 mmol), tBuOLi (160 mg, 2.0 mmol), and DMPU (0.5 mL), 125° C., 12 hours. After column chromatography (hexanes) 40 mg (18%) of a colorless oil was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952207B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-569b3fc85cac446496ab64546f0594df |
| Source note | uspto-grants-2015_02 |