Formic Acid → 4-(4'-Aminoethyl-biphenyl-3-yloxy)-pyrimidine-2-carbonitrile

HRID 184906Notes

Reaction equation

HRID 184906 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH2:8][CH2:9][c:10]1[cH:11][cH:12][c:13](-[c:16]2[cH:17][c:18]([O:22][c:23]3[n:24][c:25]([C:29]#[N:30])[n:26][cH:27][cH:28]3)[cH:19][cH:20][cH:21]2)[cH:14][cH:15]1)([CH3:5])([CH3:6])[CH3:31].[CH:32]([OH:33])=[O:34]>>[NH2:7][CH2:8][CH2:9][c:10]1[cH:11][cH:12][c:13](-[c:16]2[cH:17][c:18]([O:22][c:23]3[n:24][c:25]([C:29]#[N:30])[n:26][cH:27][cH:28]3)[cH:19][cH:20][cH:21]2)[cH:14][cH:15]1

Participants

3

Reactant 2

HCID 284Formic AcidHCID 68579160{2-[3'-(2-Cyano-pyrimidin-4-yloxy)-biphenyl-4-yl]-ethyl}carbamic acid tert-butyl ester

Product 1

HCID 159811724-(4'-Aminoethyl-biphenyl-3-yloxy)-pyrimidine-2-carbonitrile

Sources & evidence

ORD record
ord-622dee13d6f94dceb1461eb0bbd0d1fa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…