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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1849076Generated: November 1, 2026

3-(Methylsulfonyl)phenylboronic acid → 1-isopropyl-5-(8-(3-(methylsulfonyl)phenyl)-4,5-dihydrobenzo[b]thieno[2,3-d]oxepin-2-yl)-1H-1,2,4-triazole

https://huagongshe.com/reaction/1849076

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Methylsulfonyl)phenylboronic acidHCID 2773542—
Reactant5-(8-Bromo-4,5-dihydro-6-oxa-1-thia-benzo[e]azulen-2-yl)-1-isopropyl-1H-[1,2,4]triazoleHCID 57900343—
Product1-isopropyl-5-(8-(3-(methylsulfonyl)phenyl)-4,5-dihydrobenzo[b]thieno[2,3-d]oxepin-2-yl)-1H-1,2,4-triazoleHCID 58204161—

Reaction Steps

Following the procedure for 114, 5 5-(8-Bromo-4,5-dihydro-6-oxa-1-thia-benzo[e]azulen-2-yl)-1-isopropyl-1H-[1,2,4]triazole was reacted with 3-methylsulfonylphenylboronic acid to give 146. MS(ESI+) 466.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08952043B2
Source datasetuspto-grants-2015_02
ORD IDord-635e03b928d14d92a97871f656c89901
Source noteuspto-grants-2015_02