HuagongsheHuagongshe Chemistry Print Report · For research reference only
Betahistine → HCID 58204250, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Betahistine | HCID 2366 | — |
| Reactant | 8-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acid | HCID 58203883 | — |
| Product | HCID 58204250 | HCID 58204250 | — |
Reaction Steps
Following the procedure for 103, 8-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acid (50.0 mg, 0.2 mmol) was reacted with N-methyl-2-(pyridine-2-yl)ethanamine (1.2 equiv) to give 169 (14.4 mg, M+1 432.1)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952043B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-d426961e62a844efb449742c57780e6c |
| Source note | uspto-grants-2015_02 |