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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1849107Generated: November 2, 2026

1-Piperazinylpyrazine → HCID 58203946, compound

https://huagongshe.com/reaction/1849107

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-PiperazinylpyrazineHCID 2734639—
Reactant8-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acidHCID 58203883—
ProductHCID 58203946HCID 58203946—

Reaction Steps

Following the procedure for 103, 8-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acid (50.0 mg, 0.2 mmol) was reacted with 2-(piperazin-1-yl)pyrazine (1.2 equiv) to give 178 (8.7 mg, M+1 460.1)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08952043B2
Source datasetuspto-grants-2015_02
ORD IDord-0cf2f102df0147e68a47418c079878f0
Source noteuspto-grants-2015_02