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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1849129Generated: October 29, 2026

HCID 7022177, compound → HCID 58204218, compound

https://huagongshe.com/reaction/1849129

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 7022177HCID 7022177—
Reactant8-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acidHCID 58203883—
ProductHCID 58204218HCID 58204218—

Reaction Steps

Following the procedure for 103, 8-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acid (50.0 mg, 0.2 mmol) was reacted with (R)-3-(trifluoromethyl)piperidine (1.2 equiv) to give 201 (M+1 449.0)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08952043B2
Source datasetuspto-grants-2015_02
ORD IDord-105ddd5e5f5448d5a97d6294c8855a84
Source noteuspto-grants-2015_02