Methyl 2-(3-(cyclopropylmethyl)-2-oxoimidazolidin-1-yl)thiazole-5-carboxylate → 2-(3-(Cyclopropylmethyl)-2-oxoimidazolidin-1-yl)thiazole-5-carboxylic acid

HRID 184926Notes

Reaction equation

HRID 184926 reaction equation
[CH2:1]([NH:2][C:3]([c:4]1[s:5][c:6]([N:7]2[CH2:8][CH2:9][N:10]([CH2:11][c:12]3[cH:13][c:14]([C:18]([O:19][CH2:20][CH3:21])=[O:22])[cH:15][cH:16][cH:17]3)[C:23]2=[O:24])[n:25][c:26]1[CH3:27])=[O:28])[c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1.[CH:35]1([CH2:38][N:39]2[C:40](=[O:53])[N:41]([c:44]3[s:45][c:46]([C:49](=[O:50])[O:51][CH3:52])[cH:47][n:48]3)[CH2:42][CH2:43]2)[CH2:36][CH2:37]1>>[CH:35]1([CH2:38][N:39]2[C:40](=[O:53])[N:41]([c:44]3[s:45][c:46]([C:49](=[O:50])[OH:51])[cH:47][n:48]3)[CH2:42][CH2:43]2)[CH2:36][CH2:37]1

Participants

3

Reactant 2

HCID 58031461Methyl 2-(3-(cyclopropylmethyl)-2-oxoimidazolidin-1-yl)thiazole-5-carboxylateHCID 59481231Ethyl 3-((3-(5-(benzylcarbamoyl)-4-methylthiazol-2-yl)-2-oxoimidazolidin-1-yl)methyl)benzoate

Product 1

HCID 580314172-(3-(Cyclopropylmethyl)-2-oxoimidazolidin-1-yl)thiazole-5-carboxylic acid

Sources & evidence

ORD record
ord-827e4953284e4b4397c91462b2fe6549
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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