HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Adamantan-1-ylmethoxy)-3-bromobenzonitrile → 4-(Adamantan-2-ylmethoxy)-3-cyclopropylbenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Adamantan-1-ylmethoxy)-3-bromobenzonitrile | HCID 86702843 | — |
| Reactant | 4-(Adamantan-2-ylmethoxy)-3-bromobenzonitrile | HCID 86702916 | — |
| Product | 4-(Adamantan-2-ylmethoxy)-3-cyclopropylbenzonitrile | HCID 86702915 | — |
Reaction Steps
Following the procedure as described in Example 39 step 1 and making variation as required to replace 4-(adamantan-1-ylmethoxy)-3-bromobenzonitrile with 4-(adamantan-2-ylmethoxy)-3-bromobenzonitrile the title compound was obtained as a colorless solid (0.68 g, 84%): MS (ES+) m/z 308.3 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952169B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-083ddc6d0cf845e1aa8598775e99d145 |
| Source note | uspto-grants-2015_02 |