HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Adamantan-1-ylmethoxy)-3-(2-methoxypyridin-3-yl)benzonitrile → 4-(Adamantan-2-ylmethoxy)-3-cyclopropylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Adamantan-1-ylmethoxy)-3-(2-methoxypyridin-3-yl)benzonitrile | HCID 86702844 | — |
| Reactant | 4-(Adamantan-2-ylmethoxy)-3-cyclopropylbenzonitrile | HCID 86702915 | — |
| Product | 4-(Adamantan-2-ylmethoxy)-3-cyclopropylbenzamide | HCID 86702917 | — |
Reaction Steps
Following the procedure as described in Example 38 step 3 and making variations as required to replace 4-(adamantan-1-ylmethoxy)-3-(2-methoxypyridin-3-yl)benzonitrile with 4-(adamantan-2-ylmethoxy)-3-cyclopropylbenzonitrile, the title compound was obtained as a colorless solid (0.62 g, 95%): MS (ES+) m/z 326.3 (M+1);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952169B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-03666a07433d4539b0a803dfc0df6ffb |
| Source note | uspto-grants-2015_02 |