Acetic Anhydride → 1-acetyl-N-{4-[(2-{[2-fluoro-5-(trifluoro methyl)phenyl]amino}-1-methyl-1H-benzimidazol-5-yl)oxy]pyridin-2-yl}piperidine-4-carboxamide
Reaction equation
[CH3:39][C:40](=[O:41])[O:42][C:43](=[O:44])[CH3:45].[F:1][c:2]1[c:3]([NH:12][c:13]2[n:14][c:15]3[c:16]([n:17]2[CH3:18])[cH:19][cH:20][c:21]([O:23][c:24]2[cH:25][c:26]([NH:30][C:31](=[O:32])[CH:33]4[CH2:34][CH2:35][NH:36][CH2:37][CH2:38]4)[n:27][cH:28][cH:29]2)[cH:22]3)[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1.[O:46]1[CH2:47][CH2:48][O:49][CH2:50][CH2:51]1>>[F:1][c:2]1[c:3]([NH:12][c:13]2[n:14][c:15]3[c:16]([n:17]2[CH3:18])[cH:19][cH:20][c:21]([O:23][c:24]2[cH:25][c:26]([NH:30][C:31](=[O:32])[CH:33]4[CH2:34][CH2:35][N:36]([C:40]([CH3:39])=[O:41])[CH2:37][CH2:38]4)[n:27][cH:28][cH:29]2)[cH:22]3)[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-4edfc7bad7d74b1182d400ddda8b9ea0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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