Hydrochloric Acid → HCID 86703647, compound

Participants

Reaction Steps

To a mixture of 2-methylallyl 3-chloro-4-(3-((2-methylallyl)oxy)cyclohexyl)- benzoate (0.153 g, 0.42 mmol) in tetrahydrofuran (2 mL) and methanol (1 mL) was added a solution of lithium hydroxide monohydrate (0.088 g, 2.10 mmol) in water (2 mL). The reaction mixture was stirred for 16 hours at ambient temperature. After dilution with dichloromethane (50 mL), 1N hydrochloric acid (5 mL) was added. The organic phase was dried over anhydrous sodium sulfate, filtered, and concentrated under reduced pressure. The title compound was obtained as a colorless solid (0.130 g, quant.) and used without further purification: MS (ES−) m/z 307.2, 309.2 (M−1).

Provenance & Evidence