Tert-butyl 4-(bicyclo[4.1.0]heptan-1-ylmethoxy)-5-chloro-2-fluorobenzoate → Tert-butyl 5-cyclopropyl-4-((3,3-dimethylcyclohexyl)oxy)-2-fluorobenzoate

Participants

Reaction Steps

Following the procedure as described in Example 342 Step 4 and making variations as required to replace tert-butyl 4-(bicyclo[4.1.0]heptan-1-ylmethoxy)-5-chloro-2-fluorobenzoate with tert-butyl 5-chloro-4-((3,3-dimethyl- cyclohexyl)oxy)-2-fluorobenzoate, the title compound was obtained as an orange oil (1.29 g, 82%): MS (ES+) m/z 385.1 (M+23).

Provenance & Evidence