Acetonitrile → 4,4,4-trifluoro-N-[1-(4-fluoro-3-propan-2-yloxyphenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-3-(trifluoromethyl)but-2-enamide
Reaction equation
[CH3:48][C:49]#[N:50].[F:1][c:2]1[c:3]([O:31][CH:32]([CH3:33])[CH3:34])[cH:4][c:5]([C:8]([CH2:9][c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)([NH2:16])[c:17]2[cH:18][c:19]([F:30])[cH:20][c:21]([O:23][C:24]([CH:25]([F:26])[F:27])([F:28])[F:29])[cH:22]2)[cH:6][cH:7]1.[F:35][C:36]([C:37](=[CH:38][C:39](=[O:40])[OH:41])[C:42]([F:43])([F:44])[F:45])([F:46])[F:47]>>[F:1][c:2]1[c:3]([O:31][CH:32]([CH3:33])[CH3:34])[cH:4][c:5]([C:8]([CH2:9][c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)([NH:16][C:39]([CH:38]=[C:37]([C:36]([F:35])([F:46])[F:47])[C:42]([F:43])([F:44])[F:45])=[O:40])[c:17]2[cH:18][c:19]([F:30])[cH:20][c:21]([O:23][C:24]([CH:25]([F:26])[F:27])([F:28])[F:29])[cH:22]2)[cH:6][cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-89c1e10c3853471ebf5041dcad7bb68b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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