1-Azetidinesulfonamide → HCID 86703783, compound

Participants

Reaction Steps

The compound was prepared in a similar manner to Example 408 from 4-((1-benzhydrylazetidin-3-yl)methoxy)-5-cyclopropyl-2-fluorobenzoic acid and azetidine-1-sulfonamide. LCMS (Method D): RT=4.74 min, m/z: 550.3 [M+H]+. 1H NMR (400 MHz, DMSO-d6) δ 11.57 (s, 1H), 7.46-7.38 (m, 4H), 7.28 (dd, J=8.3, 6.8 Hz, 4H), 7.22-7.13 (m, 3H), 6.99-6.87 (m, 1H), 4.46 (s, 1H), 4.21 (d, J=6.1 Hz, 2H), 3.97 (s, 3H), 3.28-3.21 (m, 2H), 3.07-2.94 (m, 2H), 2.91-2.81 (m, 1H), 2.20-1.99 (m, 3H), 1.25 (d, J=6.9 Hz, 1H), 0.93-0.85 (m, 2H), 0.70-0.62 (m, 2H).

Provenance & Evidence