反应详情

The compound (2.9 g, 14.2 mmol) obtained in Step 2 was dissolved in N,N-dimethylsulfoneamide (70 mL), and 3-nitrophenol (1.9 g, 14.2 mmol) and cesium carbonate (9.2 g, 28.4 mmol) were added thereto, followed by stirring room temperature for 1 hour. After the reaction was complete, distilled water was added to the reaction mixture, and the resulting solid was filtered under a reduced pressure with washing with distilled water. The resulting solid was dried under a reduced pressure to obtain the title compound (yield: 4.0 g, 91.8%).

1. additionwere added
2. distillationdistilled water
3. additionwas added to the reaction mixture
4. filtrationthe resulting solid was filtered under a reduced pressure
5. washwith washing with distilled water
6. customThe resulting solid was dried under a reduced pressure