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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 185008Generated: November 1, 2026

Toluene → 2-[(2-Benzyl-5,5-difluoro-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-3-yl)methyl]isoindole-1,3-dione

https://huagongshe.com/reaction/185008

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantPhthalimideHCID 6809—
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
Reactantethyl N-ethoxycarbonyliminocarbamateHCID 220568—
Reactant(3-Benzyl-7,7-difluoro-3-azabicyclo[3.3.0]oct-2-yl)-methanolHCID 66703990—
Product2-[(2-Benzyl-5,5-difluoro-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrol-3-yl)methyl]isoindole-1,3-dioneHCID 66703914—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-238fc15719f74e7f9fd190d66c4608ed
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)