2-(Trifluoromethyl)benzeneboronic acid → HCID 67344917, compound

HRID 1850084Notes

Reaction equation

HRID 1850084 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:11][CH:10]([O:12][C:13]2[CH:18]=[C:17](Br)[CH:16]=[CH:15][C:14]=2[C:20]#[N:21])[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[F:22][C:23]([F:34])([F:33])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=1B(O)O>>[C:1]([O:5][C:6]([N:8]1[CH2:11][CH:10]([O:12][C:13]2[CH:18]=[C:17]([C:25]3[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=3[C:23]([F:34])([F:33])[F:22])[CH:16]=[CH:15][C:14]=2[C:20]#[N:21])[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 27343872-(Trifluoromethyl)benzeneboronic acidHCID 673451981,1-Dimethylethyl 3-(5-bromo-2-cyanophenoxy)-1-azetidinecarboxylate

Product 1

HCID 67344917HCID 67344917, compound

Procedure

Prepared from the title compound of Step A according to Example 1 Step E using 2-trifluoromethylphenylboronic acid.

Sources & evidence

ORD record
ord-694641c5306845b4bb02b4a4549b3d08
Source dataset
uspto-grants-2015_02
Patent number
US08957059B2

Reaction notes

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