3-Oxetanone → HCID 86730140, compound

HRID 1850111Notes

Reaction equation

HRID 1850111 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([N:8]2[CH:12]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:11]3(CCOC[CH2:19]3)[O:10][C:9]2=[O:24])[CH:5]=[CH:4][N:3]=1.[O:25]1CC(=O)[CH2:26]1>>[Cl:1][C:2]1[N:7]=[C:6]([N:8]2[CH:12]([C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=3)[C:11]3([CH2:19][O:25][CH2:26]3)[O:10][C:9]2=[O:24])[CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 150242543-OxetanoneHCID 86730139HCID 86730139, compound

Product 1

HCID 86730140HCID 86730140, compound

Procedure

Prepared using similar methods as described above for 3-(2-chloropyrimidin-4-yl)-4-phenyl-1,8-dioxa-3-azaspiro[4.5]decan-2-one, but starting with oxetan-3-one. LCMS m/z 318.1 (M+H)+, Rt 0.78 min.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-d0f6796e551240f5819ad64c40b38277
Source dataset
uspto-grants-2015_02
Patent number
US08957068B2

Reaction notes

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