HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(N-Boc-amino)piperidine → tert-butyl 1-(4-((S)-1-(4-((S)-4-isopropyl-2-oxooxazolidin-3-yl)pyrimidin-2-ylamino)ethyl)benzyl)piperidin-4-ylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(N-Boc-amino)piperidine | HCID 723833 | — |
| Reactant | 4-((S)-1-(4-((S)-4-isopropyl-2-oxooxazolidin-3-yl)pyrimidin-2-ylamino)ethyl)benzaldehyde | HCID 86730159 | — |
| Product | tert-butyl 1-(4-((S)-1-(4-((S)-4-isopropyl-2-oxooxazolidin-3-yl)pyrimidin-2-ylamino)ethyl)benzyl)piperidin-4-ylcarbamate | HCID 86730211 | — |
Reaction Steps
Title compound was prepared as a white solid (32 mg, 59% yield), with procedures similar to those used to prepare Intermediate 128, but utilizing 4-((S)-1-(4-((S)-4-isopropyl-2-oxooxazolidin-3-yl)pyrimidin-2-ylamino)ethyl)benzaldehyde and tert-butyl piperidin-4-ylcarbamate. MS m/z 539.4 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957068B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-da3eeb11422e4a51b35f91eec2910069 |
| Source note | uspto-grants-2015_02 |