HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropanol → HCID 86730229, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | HCID 86730231 | HCID 86730231 | — |
| Solvent | Carbon Dioxide | HCID 280 | — |
| Product | HCID 86730229 | HCID 86730229 | — |
| Product | HCID 86730230 | HCID 86730230 | — |
Reaction Steps
A mixture of (4S)-3-(2-((1-(3,4-dimethoxyphenyl)ethyl)amino)pyrimidin-4-yl)-4-isopropyloxazolidin-2-one (example 118) was resolved on a column (AS-H 4.6×100 mm) using 30% iPrOH in CO2 to give (S)-3-(2-((R)-1-(3,4-dimethoxyphenyl)ethylamino)pyrimidin-4-yl)-4-isopropyloxazolidin-2-one and (S)-3-(2-((S)-1-(3,4-dimethoxyphenyl)ethylamino)pyrimidin-4-yl)-4-isopropyloxazolidin-2-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957068B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-671ed8a907784a778ef684633b9918b9 |
| Source note | uspto-grants-2015_02 |