HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropanol → HCID 86730239, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | HCID 86730241 | HCID 86730241 | — |
| Solvent | Carbon Dioxide | HCID 280 | — |
| Product | HCID 86730239 | HCID 86730239 | — |
| Product | HCID 86730240 | HCID 86730240 | — |
Reaction Steps
(4S)-3-(2-(1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)ethylamino)pyrimidin-4-yl)-4-isopropyloxazolidin-2-one (example 130, 52 mg) was resolved on a column (IA 4.6×100 mm) using 40% iPrOH in CO2 to give (S)-3-(2-((R)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)ethylamino)pyrimidin-4-yl)-4-isopropyloxazolidin-2-one and (S)-3-(2-((S)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)ethylamino)pyrimidin-4-yl)-4-isopropyloxazolidin-2-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957068B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-6d11125049824f23bde617303456ee75 |
| Source note | uspto-grants-2015_02 |