HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 86730247, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | HCID 86730249 | HCID 86730249 | — |
| Solvent | Carbon Dioxide | HCID 280 | — |
| Product | HCID 86730247 | HCID 86730247 | — |
| Product | HCID 86730248 | HCID 86730248 | — |
Reaction Steps
4,4-dimethyl-3-(2-(1-(4-(piperidin-1-yl)phenyl)ethylamino)pyrimidin-4-yl)oxazolidin-2-one (example 183, 70 mg) was resolved on a column (IA 4.6×100 mm) using 40% MeOH in CO2 to give (S)-4,4-dimethyl-3-(2-(1-(4-(piperidin-1-yl)phenyl)ethylamino)pyrimidin-4-yl)oxazolidin-2-one and (R)-4,4-dimethyl-3-(2-(1-(4-(piperidin-1-yl)phenyl)ethylamino)pyrimidin-4-yl)oxazolidin-2-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957068B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-69cc77f4e5274046af839e97ada40c55 |
| Source note | uspto-grants-2015_02 |