HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloride methanol → [1-(3-Azetidin-3-YL-pyrazin-2-YL)-piperidin-4-YL]-methanol hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloride methanol | HCID 21893726 | — |
| Reactant | HCID 58547227 | HCID 58547227 | — |
| Product | [1-(3-Azetidin-3-YL-pyrazin-2-YL)-piperidin-4-YL]-methanol hydrochloride | HCID 67469292 | 98% |
Reaction Steps
A solution of (36) (557 mg, 1.6 mmol) in 4N HCl/MeOH (20 mL) was stirred at RT for 30 min. The reaction mixture was concentrated to give (37) (450 mg, 1.58 mmol, yield 98%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957073B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-b6cc3478763440b485420695ef72acb5 |
| Source note | uspto-grants-2015_02 |