HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-chlorotoluene → HCID 59485060, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-chlorotoluene | HCID 609899 | — |
| Reactant | 1-(2,2,4,6,7-Pentamethyl-2,3-dihydro-1-benzofuran-5-yl)piperazine | HCID 66759731 | — |
| Product | HCID 59485060 | HCID 59485060 | 15% |
Reaction Steps
By using 1-(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)piperazine (274 mg, 1.00 mmol) synthesized in Reference example 61 and 4-bromo-1-chloro-2-methylbenzene (308 mg, 1.50 mmol), the reaction was carried out in the same manner as Example 23 to obtain the title compound 60 mg (yield 15%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957069B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-973d42f3b2aa47c69332578f27953387 |
| Source note | uspto-grants-2015_02 |