HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-bromo-4-(trifluoromethyl)- → HCID 59484999, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-bromo-4-(trifluoromethyl)- | HCID 67872 | — |
| Reactant | HCID 66759462 | HCID 66759462 | — |
| Product | HCID 59484999 | HCID 59484999 | 55.1% |
Reaction Steps
By using 1-(7-methoxy-2,4,6-trimethyl-2,3-dihydro-1-benzofuran-5-yl)piperazine (552 mg, 2.0 mmol) synthesized in Reference example 88 and 1-bromo-4-(trifluoromethyl)benzene (900 mg, 4.0 mmol), the reaction was carried out in the same manner as Example 23 to synthesize the title compound 463 mg (yield 55%). Melting point was 142 to 145° C. (ethanol-water).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957069B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-d9af92862e5940a4bd7198f18f14ef52 |
| Source note | uspto-grants-2015_02 |