Triethyl methanetricarboxylate → HCID 54679210, compound

HRID 1850808Notes

Reaction equation

HRID 1850808 reaction equation
[CH2:1]([NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[CH2:14]([O:16][C:17]([CH:19]([C:25](OCC)=[O:26])[C:20](OCC)=[O:21])=[O:18])[CH3:15]>C(O)C>[CH2:1]([N:7]1[C:8]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[C:25]([OH:26])=[C:19]([C:17]([O:16][CH2:14][CH3:15])=[O:18])[C:20]1=[O:21])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

4

Reactant 2

HCID 80471Triethyl methanetricarboxylateHCID 138340N-Hexylaniline

Product 1

HCID 54679210HCID 54679210, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a round-bottomed flask equipped with a condenser, N-hexylaniline (355 mg, 2 mmol) is added to a solution of methanetricarboxylic acid triethyl ester (1.35 ml, 6.4 mmol). The resulting reaction mixture is placed in a CEM Discovery microwave oven and irradiated in the open round-bottomed flask, and then the ethanol formed is distilled off (the parameters are the following: power=250 W, temperature=225° C., execution time=5 min, hold time=15 min).

Workup

  1. customIn a round-bottomed flask equipped with a condenser
  2. customThe resulting reaction mixture
  3. customirradiated in the open round-bottomed flask
  4. distillationis distilled off (the parameters
  5. custompower=250 W, temperature=225° C., execution time=5 min
  6. customtime=15 min

Sources & evidence

ORD record
ord-3140bf1357d04e6fa6fe4d6cf902982b
Source dataset
uspto-grants-2015_02
Patent number
US08957091B2

Reaction notes

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