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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1850846Generated: October 25, 2026

3-Methoxyphenethylamine → 1-[1-(4-Chlorophenyl)cyclobutyl]-3,4-dihydroisoquinolin-6-ol

https://huagongshe.com/reaction/1850846

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethoxyphenethylamineHCID 74866—
Reactant1-[1-(4-Chlorophenyl)cyclobutyl]-3,4-dihydroisoquinolin-7-olHCID 58246243—
Product1-[1-(4-Chlorophenyl)cyclobutyl]-3,4-dihydroisoquinolin-6-olHCID 136019354—

Reaction Steps

1-[1-(4-Chlorophenyl)cyclobutyl]-3,4-dihydroisoquinolin-6-ol was prepared analogously to 1-[1-(4-chlorophenyl)cyclobutyl]-3,4-dihydroisoquinolin-7-ol (cf. example 82) using 2-(3-methoxyphenyl)ethanamine in place of 2-(4-methoxyphenyl)ethanamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08957089B2
Source datasetuspto-grants-2015_02
ORD IDord-89540c92a3c54ae49fae999c8523b331
Source noteuspto-grants-2015_02