Butanoic acid, 2-bromo-, methyl ester → HCID 86709158, compound

HRID 1851101Notes

Reaction equation

HRID 1851101 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[C:8]([C:11]([F:14])([F:13])[F:12])[C:7]([C:15]#[N:16])=[CH:6][CH:5]=2.Br[CH:18]([CH2:23][CH3:24])[C:19]([O:21][CH3:22])=[O:20]>>[C:15]([C:7]1[C:8]([C:11]([F:12])([F:14])[F:13])=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]([CH:18]([CH2:23][CH3:24])[C:19]([O:21][CH3:22])=[O:20])[C:2]([CH3:1])=[CH:10]2)#[N:16]

Participants

3

Reactant 2

HCID 95577Butanoic acid, 2-bromo-, methyl esterHCID 533093462-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Product 1

HCID 86709158HCID 86709158, compound

Procedure

Synthesized in a manner similar to Example 1 using 2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile and methyl 2-bromobutanoate: MS (ESI): m/z 325 (MH+).

Sources & evidence

ORD record
ord-ecd86bafc8ab4a23980f7fef49c2c17a
Source dataset
uspto-grants-2015_02
Patent number
US08957104B2

Reaction notes

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