Methyl 2-bromopropionate → HCID 86709166, compound

HRID 1851109Notes

Reaction equation

HRID 1851109 reaction equation
[F:1][CH:2]([F:16])[C:3]1[NH:4][C:5]2[C:10]([CH:11]=1)=[C:9]([C:12]#[N:13])[C:8]([C:14]#[N:15])=[CH:7][CH:6]=2.Br[CH:18]([CH3:23])[C:19]([O:21][CH3:22])=[O:20]>>[C:12]([C:9]1[C:8]([C:14]#[N:15])=[CH:7][CH:6]=[C:5]2[C:10]=1[CH:11]=[C:3]([CH:2]([F:1])[F:16])[N:4]2[CH:18]([CH3:23])[C:19]([O:21][CH3:22])=[O:20])#[N:13]

Participants

3

Reactant 2

HCID 95576Methyl 2-bromopropionateHCID 578003412-(difluoromethyl)-1H-indole-4,5-dicarbonitrile

Product 1

HCID 86709166HCID 86709166, compound

Procedure

Synthesized in a manner similar to Example 1 using 2-(difluoromethyl)-1H-indole-4,5-dicarbonitrile (see, for example, US2008139631A1) and methyl 2-bromopropanoate: MS (ESI): m/z 304 (M+H).

Sources & evidence

ORD record
ord-ee81e560bab344aabadf4fbf7e8c5218
Source dataset
uspto-grants-2015_02
Patent number
US08957104B2

Reaction notes

Loading…