Butanoic acid, 2-bromo-, methyl ester → HCID 86709173, compound

HRID 1851118Notes

Reaction equation

HRID 1851118 reaction equation
[F:1][C:2]([F:15])([F:14])[C:3]1[C:11]([C:12]#[N:13])=[CH:10][CH:9]=[C:8]2[C:4]=1[CH:5]=[CH:6][NH:7]2.Br[CH:17]([CH2:22][CH3:23])[C:18]([O:20][CH3:21])=[O:19]>>[C:12]([C:11]1[C:3]([C:2]([F:14])([F:1])[F:15])=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([CH:17]([CH2:22][CH3:23])[C:18]([O:20][CH3:21])=[O:19])[CH:6]=[CH:5]2)#[N:13]

Participants

3

Reactant 2

HCID 95577Butanoic acid, 2-bromo-, methyl esterHCID 674054494-(trifluoromethyl)-1H-indole-5-carbonitrile

Product 1

HCID 86709173HCID 86709173, compound

Procedure

Synthesized in a manner similar to Example 1 using 4-(trifluoromethyl)-1H-indole-5-carbonitrile and methyl 2-bromobutanoate: MS (ESI): m/z 311 (MH+).

Sources & evidence

ORD record
ord-b3b0defb12ac4fea89048b3184ee9f2a
Source dataset
uspto-grants-2015_02
Patent number
US08957104B2

Reaction notes

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