HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-1-(methylthio)propan-2-amine → (R)-4-Chloro-1-(1-(methylthio)propan-2-yl)-1H-indole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-1-(methylthio)propan-2-amine | HCID 57886830 | — |
| Reactant | HCID 86709177 | HCID 86709177 | — |
| Product | (R)-4-Chloro-1-(1-(methylthio)propan-2-yl)-1H-indole-5-carbonitrile | HCID 86709183 | — |
Reaction Steps
Synthesized in a manner similar to Example 36 using 2-chloro-4-fluoro-3-((trimethylsilyl)ethynyl)benzonitrile (Example 32B) and (R)-1-(methylthio)propan-2-amine (Example 27C): MS (ESI): m/z 265 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957104B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-64cdae85ac9348b1b26f6c77b6fd5d8c |
| Source note | uspto-grants-2015_02 |