HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl phenylmalonate → HCID 178517378, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl phenylmalonate | HCID 66514 | — |
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | Bis(2-amino-1H-imidazole) sulphate | HCID 135136 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178517378 | HCID 178517378 | — |
Reaction Steps
18.3 g (0.0776 mol) diethylphenylmalonate and 20.5 g (0.0776 mol) 2-aminoimidazole sulfate were dissolved in 93 mL DMF and 35 mL DBU and the mixture was heated to 100° C. for 15 h. The solvent was removed, the residue dissolved in water and re-precipitated by adjusting the pH to 1 with 2 mol/l HCl. The precipitate was collected by filtration to obtain the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957064B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-dc949112f7bc4bc1af131432c1a45ad0 |
| Source note | uspto-grants-2015_02 |