7-(4-Formylphenyl)-6-phenylimidazo[1,2-a]pyrimidine-3-carbonitrile → 4-(3-Methyl-6-phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde

HRID 1851178Notes

Reaction equation

HRID 1851178 reaction equation
[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:13][N:12]3[C:21]([C:24]#N)=[CH:22][N:23]=[C:11]3[N:10]=2)=[CH:5][CH:4]=1)=[O:2].C[Zn]Cl>>[CH3:24][C:21]1[N:12]2[CH:13]=[C:14]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[C:9]([C:6]3[CH:7]=[CH:8][C:3]([CH:1]=[O:2])=[CH:4][CH:5]=3)=[N:10][C:11]2=[N:23][CH:22]=1

Participants

3

Reactant 2

HCID 866306577-(4-Formylphenyl)-6-phenylimidazo[1,2-a]pyrimidine-3-carbonitrileHCID 178477798HCID 178477798, compound

Product 1

HCID 867030494-(3-Methyl-6-phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde

Procedure

The compound was synthesized in a manner according to 7-(4-formylphenyl)-6-phenylimidazo[1,2-a]pyrimidine-3-carbonitrile by using MeZnCl instead of Zn and ZnCN2.

Workup

  1. customThe compound was synthesized in a manner

Sources & evidence

ORD record
ord-e70d6fedf0b44df0b3bf97915db137ca
Source dataset
uspto-grants-2015_02
Patent number
US08957064B2

Reaction notes

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