Ethylamine → HCID 86703040, compound

Participants

Reaction Conditions

Reaction Steps

To 90 mg 4-(2-bromo-6-phenyl[1,2,4]triazolo[1,5-a]pyrimidin-5-yl)benzaldehyde (prepared as described above) in 2 mL NMP were added 0.71 mL ethylamine. The mixture was heated under microwave irradiation to 100° C. for 80 min and then overnight at 100° C. under conventional heating. On cooling the reaction was diluted with water and extracted with EtOAc. The organic phase was washed with brine, dried and concentrated in vacuo to give the crude title compound as an orange oil which was used in the next step without further purification.

Provenance & Evidence