HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(6-Phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde → 2-{1-[4-(6-phenyl-imidazo[1,2-a]pyrimidin-7-yl)-benzyl]-piperidin-4-yl}-3H-imidazo[4,5-b]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(6-Phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde | HCID 86630655 | — |
| Reactant | HCID 178478275 | HCID 178478275 | — |
| Product | 2-{1-[4-(6-phenyl-imidazo[1,2-a]pyrimidin-7-yl)-benzyl]-piperidin-4-yl}-3H-imidazo[4,5-b]pyridine | HCID 178420105 | 68.4% |
Reaction Steps
By reacting 150 mg (0.5 mmol) 4-(6-phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde with 122 mg (0.6 mmol) 2-piperidine-4-yl-3H-imidazo[4,5-b]pyridine hydrochloride salt as described in example 6.0 the desired compound (166 mg) was obtained after purification on silicagel.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957064B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-5f1883dd6ed548b9bdc131ab7bc9e19f |
| Source note | uspto-grants-2015_02 |