HRID1851262

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21198026

2-(4-Piperidinyl)quinoxaline

C13H15N3

HCID86630655

未命名化合物

PRODUCTS

生成物

结构：c1ccc(-c2cn3ccnc3nc2-c2ccc(CN3CCC(c4cnc5ccccc5n4)CC3)cc2)cc1

HCID68751737

未命名化合物

收率 33.2%

PROCEDURE

实验过程

160 mg (0.53 mmol) 4-(6-phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde and 182 mg (0.64 mmol) 2-piperidine-4-yl-quinoxaline were reacted for two days at room temperature and purified as described in example 6.0. 87.3 mg of the desired compound were obtained.

WORKUP

后处理

custompurified

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-56196640d83f458796e3f105b4258778
来源数据集: uspto-grants-2015_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08957064B2
来源说明: uspto-grants-2015_02

反应 SMILES

[C:1]1([C:7]2[C:8]([C:16]3[CH:23]=[CH:22][C:19]([CH:20]=O)=[CH:18][CH:17]=3)=[N:9][C:10]3[N:11]([CH:13]=[CH:14][N:15]=3)[CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH:24]1[CH2:29][CH2:28][CH:27]([C:30]2[CH:39]=[N:38][C:37]3[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=3)[N:31]=2)[CH2:26][CH2:25]1>>[C:1]1([C:7]2[C:8]([C:16]3[CH:23]=[CH:22][C:19]([CH2:20][N:24]4[CH2:25][CH2:26][CH:27]([C:30]5[CH:39]=[N:38][C:37]6[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=6)[N:31]=5)[CH2:28][CH2:29]4)=[CH:18][CH:17]=3)=[N:9][C:10]3[N:11]([CH:13]=[CH:14][N:15]=3)[CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1