HRID1851282

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21198026

2-(4-Piperidinyl)quinoxaline

C13H15N3

结构：O=Cc1ccc(-c2nc3nccn3cc2-c2ccc(F)cc2)cc1

HCID86703020

未命名化合物

PRODUCTS

生成物

结构：Fc1ccc(-c2cn3ccnc3nc2-c2ccc(CN3CCC(c4cnc5ccccc5n4)CC3)cc2)cc1

HCID68753206

未命名化合物

PROCEDURE

实验过程

The compound is prepared in analogy to example 33.0. 216 mg (0.756 mmol) 2-Piperidine-4-ylquinoxaline are reacted with 200 mg (0.63 mmol) 4-[6-(4-fluorophenyl)-imidazo[1,2-a]pyrimidin-7-yl]-benzaldehyde. After the usual work-up and purification 201 mg (58.9%) of the title compound are obtained.

WORKUP

后处理

customThe compound is prepared in analogy to example 33.0
customAfter the usual work-up and purification 201 mg (58.9%) of the title compound
customare obtained

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-10b308f7e25c4ee7b87c81629f48adc5
来源数据集: uspto-grants-2015_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08957064B2
来源说明: uspto-grants-2015_02

反应 SMILES

[NH:1]1[CH2:6][CH2:5][CH:4]([C:7]2[CH:16]=[N:15][C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[N:8]=2)[CH2:3][CH2:2]1.[F:17][C:18]1[CH:23]=[CH:22][C:21]([C:24]2[C:25]([C:33]3[CH:40]=[CH:39][C:36]([CH:37]=O)=[CH:35][CH:34]=3)=[N:26][C:27]3[N:28]([CH:30]=[CH:31][N:32]=3)[CH:29]=2)=[CH:20][CH:19]=1>>[F:17][C:18]1[CH:19]=[CH:20][C:21]([C:24]2[C:25]([C:33]3[CH:40]=[CH:39][C:36]([CH2:37][N:1]4[CH2:2][CH2:3][CH:4]([C:7]5[CH:16]=[N:15][C:14]6[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=6)[N:8]=5)[CH2:5][CH2:6]4)=[CH:35][CH:34]=3)=[N:26][C:27]3[N:28]([CH:30]=[CH:31][N:32]=3)[CH:29]=2)=[CH:22][CH:23]=1