HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(5-Azetidine-3-yl-[1,2,4]triazole-3-yl)-6-methylpyridine → HCID 178424644, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(5-Azetidine-3-yl-[1,2,4]triazole-3-yl)-6-methylpyridine | HCID 68753485 | — |
| Reactant | 4-(2-Cyclopropyl-6-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl)benzaldehyde | HCID 86703027 | — |
| Product | HCID 178424644 | HCID 178424644 | — |
Reaction Steps
The compound is prepared in analogy to example 40.0. 211.6 mg 2-(5-Azetidine-3-yl-[1,2,4]triazole-3-yl)-6-methylpyridine×2HCl (60% pure) are reacted with 250 mg (0.73 mmol) 4-(2-cyclopropyl-6-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl)benzaldehyde (intermediate example 4.0) After the usual work-up and purification 97 mg (23.3%) of the desired compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957064B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-a8f9a09d2870458cbbac41acbceee578 |
| Source note | uspto-grants-2015_02 |