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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1851310Generated: November 2, 2026

2-(5-Azetidine-3-yl-[1,2,4]triazole-3-yl)-6-methylpyridine → HCID 178424650, compound

https://huagongshe.com/reaction/1851310

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(5-Azetidine-3-yl-[1,2,4]triazole-3-yl)-6-methylpyridineHCID 68753485—
Reactant4-(2-Methyl-5-isopropylamino-6-phenyl-imidazo[1,2-a]pyrimidin-7-yl)-benzaldehydeHCID 86703057—
ProductHCID 178424650HCID 178424650—

Reaction Steps

The compound is prepared in analogy to example 64. 399.3 mg 2-(5-Azetidine-3-yl-[1,2,4]triazole-3-yl)-6-methylpyridine×2HCl (60% pure) are reacted with 280 mg (0.76 mmol) 4-(2-methyl-5-isopropylamino-6-phenyl-imidazo[1,2-a]pyrimidin-7-yl)-benzaldehyde to yield finally after HPLC purification 10.4 mg (2.34%) of the desired compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08957064B2
Source datasetuspto-grants-2015_02
ORD IDord-e7d374c509df4b2295442f02d54e6c60
Source noteuspto-grants-2015_02