Dimethyl Sulfoxide → (4-{[4-Cyclopropyl-2-(4-trifluoromethyl-phenyl)-pyrimidin-5-ylmethyl]-methyl-amino}-2-methyl-phenoxy)-acetic acid methyl ester
Reaction equation
[CH3:22][O:23][C:24]([CH2:25][O:26][c:27]1[c:28]([CH3:35])[cH:29][c:30]([NH:33][CH3:34])[cH:31][cH:32]1)=[O:36].[CH3:39][S:40]([CH3:41])=[O:42].[Cl:1][CH2:2][c:3]1[c:4]([CH:19]2[CH2:20][CH2:21]2)[n:5][c:6](-[c:9]2[cH:10][cH:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]2)[n:7][cH:8]1.[I-:38].[Na+:37]>>[CH2:2]([c:3]1[c:4]([CH:19]2[CH2:20][CH2:21]2)[n:5][c:6](-[c:9]2[cH:10][cH:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]2)[n:7][cH:8]1)[N:33]([c:30]1[cH:29][c:28]([CH3:35])[c:27]([O:26][CH2:25][C:24]([O:23][CH3:22])=[O:36])[cH:32][cH:31]1)[CH3:34]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-0357d800bcb648ce8410a3e1edaad24d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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