Ethanol → HCID 78596803, compound

HRID 1851347Notes

Reaction equation

HRID 1851347 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][NH2:11])([O-:3])=[O:2].[N:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[C:18](=O)[CH3:19].S(=O)(=O)(O)O.C(O)C>O>[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][N:11]=[C:18]([C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][N:12]=1)[CH3:19])([O-:3])=[O:2]

Participants

6

Reactant 4

HCID 702EthanolHCID 1118Sulfuric AcidHCID 142862-AcetylpyridineHCID 3314739(2-Nitrophenyl)hydrazine

Product 1

HCID 78596803HCID 78596803, compoundYield 85%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of (2-nitrophenyl)hydrazine (2.00 g), 1-(pyridin-2-yl)ethanone (1.67 g), sulfuric acid (0.73 mL) and ethanol (50 mL) was heated under reflux for 1 hr. Water was added to the reaction mixture, and the obtained crystals were filtrated, washed with water and dried to give the title compound (2.84 g, 85%) as brown crystals. melting point 145-146° C.

Workup

  1. temperaturewas heated
  2. temperatureunder reflux for 1 hr
  3. filtrationthe obtained crystals were filtrated
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-895c42952b06446cbfe551d2ac1368a9
Source dataset
uspto-grants-2015_02
Patent number
US08957070B2

Reaction notes

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