Lawesson's reagent → HCID 57475963, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 7-[isopropyl(2-thienylsulfonyl)amino]-1H-indole-2-carboxamide (320 mg), Lawesson's reagent (213 mg) and tetrahydrofuran (5 mL) was stirred at 70° C. for 1 hr. The reaction mixture was concentrated under reduced pressure, and the residue was crystallized from a methylene chloride.toluene mixture and washed with hexane to give the title compound (148 mg, yield 44%) as crystals. melting point 204-205° C.

Provenance & Evidence