Ethyl Acetate → HCID 57901692, compound

Participants

Reaction Steps

A solution of 2-(chloromethyl)-N-methyl-N-[2-(1,3-thiazol-2-yl)-1H-indol-7-yl]thiophene-3-sulfonamide (240 mg) in triethyl phosphite (5 mL) was stirred at 100° C. for 1 hr. The reaction mixture was subjected to silica gel column chromatography (ethyl acetate) to give the title compound (67 mg, yield 25%) as a pale-yellow amorphous. M+1=526.

Provenance & Evidence