HCID 58019132, compound → HCID 58019140, compound

HRID 1851732Notes

Reaction equation

HRID 1851732 reaction equation
[F:1][C:2]([F:24])=[CH:3][CH:4]1[CH2:8][N:7]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][C:11]=2[O:18][CH3:19])[C:6](=[O:20])[CH:5]1C(O)=O>C(C(C)=O)C(C)C>[F:24][C:2]([F:1])=[CH:3][CH:4]1[CH2:8][N:7]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][C:11]=2[O:18][CH3:19])[C:6](=[O:20])[CH2:5]1

Participants

3

Reactant 1

HCID 58019132HCID 58019132, compound

Product 1

HCID 58019140HCID 58019140, compound

Reagents, catalysts & solvents 1

HCID 7909Methyl Isobutyl KetoneSolvent

Conditions

Temperature
116 °C

Procedure

A suspension of (K) in methyl isobutyl ketone (MIBK-5 L) is heated at 116° C. overnight. Evaporation of the solvent gives 564 g of (IIIc). The product is used in the next reaction without further purification.

Workup

  1. customEvaporation of the solvent
  2. customgives 564 g of (IIIc)
  3. customThe product is used in the next reaction without further purification

Sources & evidence

ORD record
ord-647cfce2f9fb430f829b4184a4a7d60b
Source dataset
uspto-grants-2015_02
Patent number
US08957226B2

Reaction notes

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