2-[6-(Ethylamino)pyridin-3-yl]-1,3-benzothiazol-6-ol → 5-(5-methoxy-1,3-benzothiazol-2-yl)-N-methylpyridin-2-amine

Participants

Role	Name	HCID	Charge
Reactant	2-[6-(Ethylamino)pyridin-3-yl]-1,3-benzothiazol-6-ol	HCID 24803888	—
Reactant	N-ethyl-5-(6-methoxy-1,3-benzothiazol-2-yl)-N-methylpyridin-2-amine	HCID 24803889	—
Product	5-(5-methoxy-1,3-benzothiazol-2-yl)-N-methylpyridin-2-amine	HCID 24803727	—

Reaction Steps

N-Ethyl-5-(6-methoxy-1,3-benzothiazol-2-yl)-N-methylpyridin-2-amine (55.4 mg, 0.185 mmol) was subjected to the procedure described for 2-[6-(ethylamino)pyridin-3-yl]-1,3-benzothiazol-6-ol. Recrystallization from methanol gave 23.7 mg of the title compound as a pale yellow solid. 1H NMR δ ppm 9.75 (s, 1 H) 8.67 (d, 1 H) 8.03 (dd, 1 H) 7.75 (d, 1 H) 7.35 (d, 1 H) 6.93 (dd, 1 H) 6.75 (d, 1 H) 3.63 (q, 2 H) 3.07 (s, 3 H) 1.11 (t, 3 H); MS m/z (M+H) 286.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08957215B2
Source dataset	uspto-grants-2015_02
ORD ID	ord-809d716cb79f426caaa698b5dc5fb8e5
Source note	uspto-grants-2015_02