HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methoxybenzothiazole → 5-(1,3-benzothiazol-2-yl)-N-methylpyridin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methoxybenzothiazole | HCID 350186 | — |
| Reactant | 2-Bromo-5-(methylthio)pyridine | HCID 11658494 | — |
| Reactant | 6-Methoxy-2-[5-(trifluoromethyl)pyridin-2-yl]-1,3-benzothiazole | HCID 24803891 | — |
| Product | 5-(1,3-benzothiazol-2-yl)-N-methylpyridin-2-amine | HCID 24804239 | — |
Reaction Steps
6-Methoxy-1,3-benzothiazole (35 mg, 0.21 mmol) and 2-bromo-5-(methylthio)pyridine (1.1 equiv) were reacted according to the procedure used for the preparation of 6-methoxy-2-[5-(trifluoromethyl)pyridin-2-yl]-1,3-benzothiazole. This gave the title compound (1 mg) as a pale yellow solid. 1H NMR (CHLOROFORM-d) δ 8.52 (d, 1 H) 8.22 (d, 1 H) 7.95 (d, 1 H) 7.67 (dd, 1 H) 7.40 (d, 1 H) 7.11 (dd, 1 H) 3.92 (s, 3 H) 2.58 (s, 3 H); MS m/z (M+H) 289.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957215B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-c1cdcb820123468f9abac8e57f27c258 |
| Source note | uspto-grants-2015_02 |