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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1851816Generated: October 26, 2026

Ethyl 1-aminocyclohexane-1-carboxylate hydrochloride → HCID 57672866, compound

https://huagongshe.com/reaction/1851816

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 1-aminocyclohexane-1-carboxylate hydrochlorideHCID 11241228—
Reactant4-(4-Propylpiperazin-1-yl)benzoic acid hydrochlorideHCID 67181841—
ProductHCID 57672866HCID 5767286665%

Reaction Steps

741 mg (3.57 mmol) of 1-aminocyclohexanecarboxylic acid ethyl ester hydrochloride was used instead of 1-aminocyclohexanecarboxylic acid methyl ester hydrochloride and 1.00 g (3.57 mmol) of 4-(4-propylpiperazin-1-yl)benzoic acid hydrochloride was used instead of 3-furancarboxylic acid in the process according to Reference example 15 to obtain 928 mg (65%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08957205B2
Source datasetuspto-grants-2015_02
ORD IDord-10139c03072d469083866c1326cbf5e7
Source noteuspto-grants-2015_02